Drug discovery services
PK & BIONALYSIS
In Vivo Pharmacokinetics:
- Rat, mice (jugular vein catheterized)
- RoA: iv, po, ip, im, sc
- Single or Repeated doses
- Tissue distribution & BBB penetration
- Blood, urine, tissues, CSF
- Metabolic profile
Analytical Services
- Structural elucidation and purity of intermediates and final products
- Identification, isolation impurities and degradation products
- Stability in hepatocytes and subcellular fractions, whole blood or plasma
- Solubility studies
Technological platforms:
UPLC-MS & UPLC-MS/MS
Semi-preparative HPLC-MS
