PK & BIOANALYSIS - DRACONIS PHARMA
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Drug discovery services

PK & BIONALYSIS

In Vivo Pharmacokinetics:

  • Rat, mice (jugular vein catheterized)
  • RoA: iv, po, ip, im, sc
  • Single or Repeated doses
  • Tissue distribution & BBB penetration
  • Blood, urine, tissues, CSF
  • Metabolic profile

Analytical Services

  • Structural elucidation and purity of intermediates and final products
  • Identification, isolation impurities and degradation products
  • Stability in hepatocytes and subcellular fractions, whole blood or plasma
  • Solubility studies

Technological platforms:
UPLC-MS & UPLC-MS/MS
Semi-preparative HPLC-MS

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